Since MEP balks at some Virtualdub filters and does not have rotoscoping capability, I have to export frames, edit them externally, and then reimport them. In this process the color changes slightly. This happens no matter the format of export. MP3 shifts towards green with less red and often has higher brightness. Huffy, a lossless codec also shows shifts, but they are different from that experienced with MP3. I can not confirm if this happens on export or import. The external editing does not change color because I can easily compare the output with the input. Since I import the original file in Huffy format, exporting it in huffy and reimporting it should not change any information.
This would seem to be a bug in MEP which needs to be fixed. I have never seen such shifts in external editors such as VirtualDub or Paint Shop Pro. It happens all the time in MEP. Sometimes the MP3 shift can be almost compensated by increasing the Red by 2 from 50 to 52, but the Huffy shifts are more complicated.
I am using a Compaq CQ5218F with AMD II X2 215, 7GB ram, Windows 7 and LG D3242P monitor, MEP 2014+.