Could you explain what you mean by "safe title frame?"
I suggest that you review the chapter about titles in MEP and try it out. Other than just a title by clicking on the T, there are specially formatted titles under the titles table in the media pool part of the screen.
A title is simply a box that is located on the screen at a default location. You decide where you want it to be located, the font, size, colour, effects, duration, fade-in/out, etc. There are no guide lines. Try playing with tittes and reading the help to understand further.